light-sheet imaging, photo-conversion, cell lineage reconstruction
Recent technological advancements in light-sheet microscopy have opened up exciting new opportunities for in toto imaging of whole developmental arcs at the cellular level. With the help of advanced fluorescent proteins, light-sheet microscopy enables the reconstruction of the entirety of embryonic development at a cellular level, allowing for image-based lineage reconstruction.
These two datasets were acquired on our OpenSiMView light-sheet microscope. You can explore the full timelapse image data here:
These two datasets were acquired on our DaXi light-sheet microscope. You can explore the full timelapse image data here: